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Ampules-all-about-

  • Ampules
  • Ampule – a small, hermetically sealed container that has a distinct, elongated neck.
    • Contains no preservative
    • Some drugs are only available in an ampule because of incompatibility with rubber or PVC components of vials
    • Parts of an Ampule


  • Parts of an Ampule: head, neck, shoulder, and body.

  • Break ring – a scored area on the neck that marks the site where a technician will break the glass to access the ampule’s contents.
  • Opening an Ampule: safe opening of an ampule can be done with a piece of gauze, sterile 70% IPA swab or a ampule breaker a small plastic cap, placed over the head of an ampule.

  • • Hold the ampule upright, clear the medication from the head and neck.
  • • Clean the neck of the ampule.
  • • Hold the ampule in the non-dominant hand, grasping the head of the ampule with the dominant hand.
  • • Exert firm but gentle pressure on the break ring to snap the ampule’s neck.
  • Withdrawing Medication from an Ampule: hold the ampule upright; bevel down in the corner near the opening.

    When the ampule is nearly empty, tilt the ampule slightly to allow easier access to the remainder of the medication.

    A filter needle should be used when drawing medication out of an ampule to avoid glass fragments.
  • Preparing a CSP with an Ampule’s Contents: similar to the process of preparation for a vial so that it can be checked by the pharmacist.

    • The pharmacist verifies the technicians work.
    • After verification the technician may proceed with the making of the CSP.
    • Lastly, the technician will need to check for leaks and signs of incompatibility and label the CSP for delivery.

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