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Compounding Sterile Products-indian-doctors

 

  • Hospitals carry out unique activities, such as the preparation, handling, and disposing of hazardous drugs.
    A major responsibility of the pharmacy tech involves compounded sterile products (CSPs).
    Aseptic technique – the processes and physical preparation methods used by sterile compounding personnel to avoid introducing pathogens, into parenteral products.
    Compliance with sterile compounding and aseptic technique standards established by USP. 

  • Sterile Supplies for IV Preparation and Administration
  • Syringes and Needles: used for withdrawing or injecting solutions during the preparation of CSPs.
    IV push (IVP) – bolus administration; rapid injection of a medication.
    Syringes: made of glass or plastic; glass – limited use, expensive; plastic – less expensive, supplied in sterile packaging, disposable.

    Main components of a syringe:
    • Syringe tip
    • Barrel – contains calibration marks
    • Rubber-tipped piston plunger
    • Syringe Selection and Measurement
    • Technicians should choose the smallest syringe that is able to hold the desired volume; at least ¾ full.
    • Technicians should count the number of marks between labeled measurement units, to get the most accurate dose.
    • The volume of solution is measured at the point of contact between the rubber-tipped piston plunger and the inside of the barrel.

    • Needles
    • Needles are made of stainless steel or aluminum. The needle size is determined by length and gauge and the lengths range from 3/8 inch to 6 inches. Gauge refers to the diameter of the opening; the larger the gauge number the smaller the opening (or size of the lumen). 
    • 31-gauge (smallest bore)
    • 13-gauge (largest bore)
    • Parts of a needleeedle shaft
    • Needle lumen
    • Needle hub
    • Syringe Selection and Measurement
    • Technicians should choose the smallest syringe that is able to hold the desired volume; at least ¾ full.
      Technicians should count the number of marks between labeled measurement units, to get the most accurate dose.
      The volume of solution is measured at the point of contact between the rubber-tipped piston plunger and the inside of the barrel.

    • Needles
    • Needles are made of stainless steel or aluminum. The needle size is determined by length and gauge and the lengths range from 3/8 inch to 6 inches. Gauge refers to the diameter of the opening; the larger the gauge number the smaller the opening (or size of the lumen). 
      • 31-gauge (smallest bore)
      • 13-gauge (largest bore)
    • Parts of a needle:
      • Needle tip
      • Bevel
      • Heel
      • Needle shaft
      • Needle lumen
      • Needle hub

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